www.ksmf.org/arhimed   arhimed@ksmf.org   [5/10/2025 12:30:53 PM] http://www.ksmf.org/arhimed/poglej.asp?id=59 Elektrofiziološko spremljanje zorenja vidne poti pri šolskih otrocih Avtor: Katja Jakopic, Katja Prokšelj Mentor: znan. sod. dr. sc. Jelka Brecelj, prof. biol. Uvod: Veliko je znanega o razvoju vidnega sistema pri majhnih otrocih. Morfološke in funkcionalne spremembe vidnega sistema so najizrazitejše v prvih mesecih življenja. Mrežnica se še razvija, vlakna v vidni poti se mielinizirajo, razvija se tudi vidna skorja. Te spremembe lahko zasledujemo z elektrofiziološkimi preiskavami - elektroretinografijo in vidnimi evociranimi potenciali. Malo je študij, ki so raziskovale spremembe vidnega sistema pri šolskih otrocih. Mnenja o tem, kdaj se razvoj vidnega sistema konca, so deljena. Namen: Namen naše raziskave je z elektrofiziološkimi metodami ugotoviti ali se vidni sistem med sedmim in osemnajstim letom še razvija. Metode: V raziskavo smo vkljucili 25 zdravih otrok starih od sedem do osemnajst let. Merili smo FERG in PERG pri draženju obeh oces hkrati ter VEP pri draženju posameznega ocesa s celim poljem ter levo in desno polovico polja. Uporabljali smo površinske elektrode. Za dražljaj smo pri FERG uporabili blisk bele svetlobe, pri PERG in VEP pa projekcijo šahovnice s 50' velikimi kvadratki. Rezultati: V raziskavi smo ugotovili, da s starostjo statisticno znacilno upadajo amplitude vala a (FERG); valov P50 in N95 (PERG); vala N70 (VEP pri draženju s celim poljem); valov N145 in N105 (VEP pri draženju z levim polpoljem); valov P100 in P135 (VEP pri draženju z desnim polpoljem). Latence valov FERG, PERG in VEP se s starostjo niso spreminjale statisticno znacilno. Zakljucki: Amplitude nekaterih valov FERG, PERG in VEP med sedmim in osemnajstim letom s starostjo upadajo. To kaže, da razvoj vidnega sistema v teh letih še ni zakljucen. «» [Abstract / English version] Electrophysiological evaluation of visual system development in schoolchildren Author: Katja Jakopic, Katja Prokšelj Mentor: znan. sod. dr. sc. Jelka Brecelj, prof. biol. Introduction: Maturation of the visual system in young children has been extensively investigated. Morphologic and functional changes of the visual system are most intense during the first months of life. There is rapid development of the retina, myelination of the visual pathway and maturation of the visual cortex. These changes can be monitored through electrophysiological methods - electroretinography and visual evoked potentials. Studies that have investigated the changes of the visual system in school children are scarce. There is a difference of opinion about the age when the development is completed. Purpose: The purpose of this study is to electrophysiologically determine whether the visual system continues to develop between the age of seven and eighteen. Methods: 25 healthy children between the age of seven and eighteen were included in the study. Surface electrodes were used. FERG and PERG were recorded binocularly. Monocular VEP recordings were made using full-field, left and right half-field stimulus. The stimulus used in PERG and VEP recordings was a pattern reversal checkerboard with 50' checks. White flash was used in FERG recordings. Results: A significant decrease was found in the amplitudes of the waves: wave a (FERG), P50 and N95 (PERG), N70 (VEP after full-field stimulation), N145 and N105 (VEP after left half-field stimulation), P100 and P135 (VEP after right half-field stimulation). There were no significant age-related changes in the latencies of FERG, PERG and VEP. Conclusions: Amplitudes of many FERG, PERG and VEP waves continue to decrease between the age of seven and eighteen. This tendency shows further development of the visual system in school children.