www.ksmf.org/arhimed   arhimed@ksmf.org   [5/10/2025 6:53:58 PM] http://www.ksmf.org/arhimed/poglej.asp?id=38 Slikanje z magnetno resonanco v diagnostiki seronegativnih spondiloartritisov Avtor: Ivana Gardaševic, Petra Hari Mentor: Prof.dr. Vladimir Jevtic Sakroiliitis je zgodnja manifestacija razlicnih seronegativnih spondiloartritisov, predvsem ankilozantnega spondilitisa , pri katerem so sakroiliakalni sklepi osnovni diagnosticni radiološki testni objekt. Pri odkrivanju sakroiliitisa so bile uporabljene razlicne radiološke tehnike od katerih sta najpomembnejši rentgensko slikanje in racunalniška tomografija Racunalniška tomografija bolje prikaže zacetne erozije subhondralne kosti. Idealna radiološka metoda naj bi postavila diagnozo še pred razvojem dokoncnih erozivnih sprememb. Namen prvega dela naše raziskave je bil ugotoviti, ali magnetno resonancna tomografija omogoca zgodnejšo diagnozo od racunalniške tomografije. Domnevamo, da je magnetno resonancna tomografija obcutljivejša od racunalniške tomografije v zgodnji diagniostiki revmatskega sakroiliitisa. Vnetne spremembe na aksialnem skeletu, ki nastanejo pri revmaticnem spondilitisu, sopomemben del seronegativnih spondiloartritisov, zlasti ankilozantnega spondilitisa. Rentgensko slikanje hrbtenice, ki se uporablja v klinicni praksi, omogoca prikaz samo kostnih patoloških spramamb. Namen drugega dela naše raziskave je bil ugotoviti kakšna je vrednost magnetno resonancne tomografije s paramagnetnim kontrastnim sredstvom Gd-DTPA za zgodnjo diagnostiko sakroiliitisa pri bolnikih s klinicno verjetnim ankilozantnim spondilitisom in za prikaz spondilitisa pri bolnikih z dokoncno diagnozo ankilozantnega spondilitisa. Domnevamo, da magnetno resonancna tomografija omogoca boljši prikaz razvoja vnetnih sprememb od do sedaj v diagnostiki obicajnega rentgenskega slikanja «» [Abstract / English version] Magnetic resonance imaging in diagnosis of seronegative spondyloarthritides Author: Ivana Gardaševic, Petra Hari Mentor: Prof.dr. Vladimir Jevtic Sacroiliitis is an early manifestation of different seronegative spondyloarthritides, particularly of ankylosing spondylitis in which the sacroiliac joints represent a basic diagnostic radiographic test object. In detecting sacroiliitis, different radiological techniques have been employed, the most important being conventional radiography, computed tomography and magnetic resonance imaging. In early diagnosis of sacroiliitis, conventional radiography and coputed tomography are used. It has been widely accepted that computed tomography is the radiological method of choice for detection of early subchondral cortical bone erosions. The ideal radiological technique should give the diagnosis before the occurrence of final erosions. The purpose in the first part of our study is to find out if the sensitivity of magnetic resonance imaging in detecting sacroiliitis could substantially exceed that of computed tomography, assuming that magnetic resonance imaging is a more sensitive diagnostic method in detecting rheumatic sacroiliitis than computed tomography. Inflammatory changes of axial skeleton as a part of rheumatic spondylitis represent an important part of seronegative spondyloarthritides, particularly ankylosing spndylitis,. Conventional radiography of spine which is being used in clinical praxis, indicates only bone destructive changes. The purpose of the second part of our study was to establish the role of magnetic resonance imaging with Gd-DTPA in early diagnosis of sacroiliitis in patients with suspected ankylosing spondylitis and those with firm diagnosis of ankylosing spondylitis. Magnetic resonance imaging is superior to conventional radiography for confirming active inflammatory changes.