www.ksmf.org/arhimed   arhimed@ksmf.org   [5/10/2025 12:45:54 PM] http://www.ksmf.org/arhimed/poglej.asp?id=19 Standardizacija nekaterih kardiocirkulatornih testov pri zdravih otrocih Avtor: Dušanka Meglic Mentor: doc. dr. Anton Grad IZHODIŠCA. Klasicni kardiocirkulatomi testi in spektralna analiza variabilnosti srcne frekvence predstavljajo zanesljivo in neinvazivno obliko testiranja funkcije avtonomnega zivcevja (AŽ) pri otrocih s sumom na okvaro le-tega. Namen te naloge je bil dolocitev razpona normalnih vrednosti in proucevanje vpliva starosti in spola na rezultate kardiovaskulamih testov. METODE. V raziskavi je sodelovalo 81 zdravih otrok, starih od 7 do 16 let. Razdelili smo jih v 5 starostnih akupin (7 do 8, 9 do 10 let,...). V vsaki skupini smo testirali 8 deklic in 8 deckov: Opravili smo že uvedene klasicne kardiocirkulatorne teste (Valsalvin preizkus, preizkus z globokim dihanjem, test stiskanja pesti, ortostatski preizkus). S spektralno analizo smo dolocili nizko- in visokofrekvencni vrh (NFV in VFV) amplitudnega spektra in izracunali razmerje NFV/VFV. REZULTATI. Za vsako starostno skupino in spol smo dolocili razpon normalnih vrednosti za Valsalvin kolicnik, respiratorni kolicnik, kolicnik stiska pesti, ortostatski kolicnik, spremembe krvnega tlaka pri testu stiska pesti (diastolnega) in pri ortostatskem preizkusu (sistolnega in diastolnega), NFV, VFV ter razmerje NFV/VFV. Statisticno pomembne negativne korelacije s starostjo smo nasli pri kolicniku stiska pesti, spremembi sistolnega tlaka pri ortostatskem preizkusu in pri razmerju NFV/VFV leže; pozitivno korelacijo s starostjo smo nasli pri VFV leze. Respiratomi kolicnik in VFV stoje sta signifikantno višja pri deklicah v starostni skupini 11 do 12 let, prav tako porast diastolnega tlaka pri deklicah v starostni skupini 15 do 16 let. ZAKLJUCKI. Kardiovaskulamo testiranjeje varna in zanesljiva oblika testiranja funkcije AZ pri otrocih. Zaradi vecje dinamicnosti sprememb pri otrocih priporocamo dolocanje referencnih vrednosti v manjših starostnih skupinah kot pri odraslih (npr. na dve leti). Pri dolocanju normalnih vrednosti je priporocljiva delitev po spolu. «» [Abstract / English version] Standardization of some cardiovascular reflex tests in healthy children Author: Dušanka Meglic Mentor: doc. dr. Anton Grad BACKGROUND. The tests of cardiovascular reflexes and heart rate variability are reliable and non-invasive and therefore useful in children with suspected failure of the autonomic nervous system (ANS). The aim of this study was to calculate normal reference values and relations between cardiovascular reflex ratios and gender and age. METHODS. The battery of cardiovascular tests was performed in 81 healthy children, aged 7 to 16 years. Valsalva, deep breathing, handgrip and orthostatic ratios were calculated and blood pressure differences were measured during handgrip (diastolic) and orthostatic (systolic and diastolic) tests. Heart rate variability was quantified by spectral analysis for low and high frequency bands (I.FB and HFB) and LFB/FgB ratio was calculated. RESULTS. Normal values of Valsalva, deep breathing, handgrip and orthostatic ratios and integrals of LFB and HFB were calculated for two years groups ( e.g. 7 - 8 years old, 9 - 10 years old,...). There were significant negative correlations between handgrip ratio, systolic blood pressure during orthostatic test, supine LFB/HFB ratio and age. There was also a significant positive correlation between supine HFB and age. Deep breathing ratio and integral of FIFB were significantly higher in female in 11 - 12 years group as well as handgrip diastolic pressure increase in female in 15 - 16 years group. CONCLUSIONS. Cardiovascular tests are safe and reliable in testing ANS in children. Age related variations are more dynamic in children than in adults and we suggest narrower age grouping limits in determining reference values in children than in adults (e.g. two years). Gender grouping should be done when determining reference values in children.